4SC AG
4SC provides operational and financial update for Q2 and 6M 2016
DGAP-News: 4SC AG / Key word(s): Half Year Results/Interim Report 4SC provides operational and financial update for Q2 and 6M 2016
Planegg-Martinsried, Germany, 11 August 2016 – 4SC AG (4SC, FSE Prime Standard: VSC) today published its consolidated financial results and provided a business update for the six months ended 30 June 2016 as well as an update on the Company’s outlook for full-year 2016. The complete half-year interim report including detailed information on 4SC’s financial results is available at our webpage under Investors & Media / Financial Reports. Business highlights in Q2 2016 and beyond
Business outlook
Development of cash balance/funds in Q2 2016 and financial forecast 4SC’s cash balance/funds totaled EUR 13,798 thousand on 30 June 2016, compared with EUR 17,121 thousand on 31 March 2016. The management of 4SC reaffirms its financial outlook for the full year 2016 of an average monthly use of cash from operations of EUR 1,200 thousand. Management further estimates that the Company’s current cash position is likely to be sufficient to fund operations into 2018. This will cover the material portions of the RESMAIN trial. 4SC projects that it will receive cash inflows from the partnerships with Yakult Honsha and Menarini AP later than originally assumed, because the detailed analysis of the results of the Phase II resminostat trial conducted by Yakult Honsha in HCC is still ongoing. This effect is largely offset by the cost savings related to the sale of 4SC’s discovery operations and the proceeds of the 4SC-205 out-licensing agreement with Link Health. Dr Daniel Vitt, Chief Scientific Officer and Chief Development Officer at 4SC, commented: “We are pleased that preparations for our own Phase II trial of resminostat (RESMAIN) in cutaneous T-cell lymphoma (CTCL) are on track to initiate this study in Q4 2016. We look forward to receiving the detailed subgroup analysis from our Japanese development partner Yakult Honsha from the recently completed Phase II trial of resminostat in combination with sorafenib as a first-line therapy in advanced HCC. These findings are particularly important for us as they will guide the future development path of resminostat in HCC. Furthermore, the highly encouraging immunological data on 4SC-202 confirm the significant potential of our second, highly promising, epigenetic candidate. This preclinical data creates additional opportunities for the clinical development of 4SC-202, including its evaluation as a combination therapy with established immunotherapy agents.” Conference call 4SC will host a public English-language conference call today at 3:00 pm CEDT, during which the management will provide information on the material developments in 6M 2016 and beyond.
Presentation material for the conference call will be available at our webpage under Investors & Media / Events & Presentations / Conference Calls & Webcasts. After the conference call, an audio recording will also be available there. – Press release ends – Related articles 16 June 2016, Resminostat boosts cancer immunotherapy 2 June 2016, 4SC at ASCO: 4SC 202 and checkpoint inhibitors – strong partners in cancer treatment 31 May 2016, 4SC enters into licensing and development partnership with Link Health for the cancer compound 4SC 205 in China
Further information About 4SC 4SC (www.4sc.com) is a biotech company dedicated to the research and development of small-molecule drugs focused on epigenetic mechanisms of action for the treatment of cancers with high unmet medical needs. These drugs are intended to provide innovative treatment options for cancer patients that are more tolerable and efficacious than existing therapies, provide a better quality of life and offer increased life expectancy. The Company’s pipeline comprises promising products that are in various stages of clinical development. 4SC’s aim is to generate future growth and enhance its enterprise value by entering into partnerships with pharmaceutical and biotech companies. Founded in 1997, 4SC had 50 employees at 30 June 2016. 4SC has been listed on the Prime Standard of the Frankfurt Stock Exchange since December 2005. About epigenetic cancer therapy Epigenetic changes modify the activation of certain genes, but not the genetic code of DNA itself, causing activation or silencing of genes. This mechanism enables differentiated cells such as those in the lungs, nerves or skin to serve very different functions despite containing identical genetic code. Epigenetic alterations are as important as genetic mutations in a cell’s transformation to cancer, and their manipulation holds great promise for cancer therapy. Epigenetic compounds such as 4SC’s resminostat and 4SC-202 may convert these epigenetic alterations back to normal. For example, treatment with epigenetic cancer compounds interrupts or combats the mechanism that is responsible for the onset of cancer, makes cancer cells visible to the body’s own immune system or renders them more responsive to immuno-oncological treatment. Epigenetics is considered as a future growth market in the field of Oncology based on its significant promise as both a monotherapy and in combined approaches with immuno-oncology drugs and other therapeutic agents. In an October 2015 report by business information publisher Grand View Research, the worldwide epigenetics market was projected to generate revenues of US-$16 billion in 2022, up from US-$ 4 billion in 2014. Forward-looking information Information set forth in this press release contains forward-looking statements, which involve a number of risks and uncertainties. The forward-looking statements contained herein represent the judgement of 4SC as of the date of this presentation. Such forward-looking statements are neither promises nor guarantees, but are subject to a variety of risks and uncertainties, many of which are beyond 4SC’s control, and which could cause actual results to differ materially from those contemplated in these forward-looking statements. 4SC expressly disclaims any obligation or undertaking to release any updates or revisions to any such statements to reflect any change in its expectations or any change in events, conditions or circumstances on which any such statement is based. 4SC Corporate Communications & Investor Relations Wolfgang Güssgen, wolfgang.guessgen@4sc.com, +49 89 700763-73 MC Services Katja Arnold, katja.arnold@mc-services.eu, +49 89 210228-40 The Ruth Group Carol Ruth, cruth@theruthgroup.com, +1 646 536 7004
2016-08-11 Dissemination of a Corporate News, transmitted by DGAP – a service of EQS Group AG. |
Language: | English | |
Company: | 4SC AG | |
Am Klopferspitz 19a | ||
82152 Planegg-Martinsried | ||
Germany | ||
Phone: | +49 (0)89 7007 63-0 | |
Fax: | +49 (0)89 7007 63-29 | |
E-mail: | public@4sc.com | |
Internet: | www.4sc.com | |
ISIN: | DE000A14KL72 | |
WKN: | A14KL7 | |
Listed: | Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Berlin, Dusseldorf, Hamburg, Munich, Stuttgart, Tradegate Exchange | |
End of News | DGAP News Service |